Toxicologie, Pharmacologie et Signalisation céllulaire - UMR-S 1124
Université Paris Descartes
45 rue des Saints Pères
75270 Paris Cedex 06
Fax : +33 (0) 1 42 86 38 68
karine.andreau@-Code to remove to avoid SPAM-univ-paris-diderot.fr
+33 1 42 86 33 60, room P434
Karine Andréau is an Associate Professor of Cellular Biology and Toxicology (Paris Diderot University) and is interested in the regulation of the cell death apoptosis mediated by environmental pollutants. Her main research activities recently have focused on the mesenchymal epithelial transition. Her teaching activities are complementary with her scientific skills and she is in charge of the first year of the Toxicology Master’s Degree Program.
Karine Andréau obtained her PhD in Cellular and Molecular Biology at University Paris Saclay (1999). During her three post-doctoral fellowships (1999-2004), she worked on the cellular and molecular pathways that are involved in the promotion or inhibition of apoptosis. She joined the Paris Diderot University in 2005 as an Associate professor and focused on the links existing between fine particulate matter (PM) and cell death.
She demonstrated that fine airborne particles prevent apoptosis by activating the aryl hydrocarbon receptor, AhR, (by the PM’s organic components) in combination with the Nrf2 pathway (induced by the PM’s metallic compounds). In 2014, she joined Team 1 of the INSERM Unit 1124 where she has investigated the mesenchymal epithelial transition and fibrosis induced by environmental pollutants (alcohol or dioxin) in human and murine liver and their potential modulations by the antiapoptotic protein DYRK1A.
Renon M, Legrand B, Blanc E, Daubigney F, Bokobza C, Mortreux M, Paul JL, Delabar JM, Rouach H, Andreau K, Janel N : Biochim Biophys Acta, 2016
Lovera-Leroux M, Crobeddu B, Kassis N, Petit PX, Janel N, Baeza-Squiban A, Andreau K : Biochimie, 2015
Andreau K, Leroux M, Bouharrour A : Biochem Res Int, 2012
Hussain S, Thomassen LC, Ferecatu I, Borot MC, Andreau K, Martens JA, Fleury J, Baeza-Squiban A, Marano F, Boland S : Part Fibre Toxicol, 2010
Ferecatu I, Borot MC, Bossard C, Leroux M, Boggetto N, Marano F, Baeza-Squiban A, Andreau K : Part Fibre Toxicol, 2010
Ambolet-Camoit A, Bui LC, Pierre S, Chevallier A, Marchand A, Coumoul X, Garlatti M, Andreau K, Barouki R, Aggerbeck M : Toxicol Sci, 2010