Toxicologie, Pharmacologie et Signalisation céllulaire - UMR-S 1124
Université Paris Descartes
45 rue des Saints Pères
75270 Paris Cedex 06
Fax : +33 (0) 1 42 86 38 68
Neuroplasticity and therapies of addictions
candice.marion@-Code to remove to avoid SPAM-inserm.fr
+33 1 42 86 38 62, room P468
Supervisor :Jacques PANTEL
After graduating from high school I followed preparatory courses in Biology, Chemistry, Physics and Earth sciences for 2 years, at the end of which I was admitted to AgroParisTech (Paris Institute of Technology for Life, Food and Environmental Sciences). There I pursued a Master of Science in Engineering for 3 years, where I acquired broad-based knowledge on agronomy, agriculture, environment, life and food sciences. During my last year in AgroParisTech I followed a Master 2 program in Nutrition & Health that ended in a 6 month-internship in the “Intestinal ecosystem, probiotics, antibiotics” team at the Faculty of Pharmacy (Paris Descartes, Paris). There I took part in a collaborative project with PiLeJe society (specialized in micronutrition) aiming at selecting a bacterial strain with prophylactic properties in cow milk’s allergy.
After graduating from AgroParisTech, I started a PhD at the Center for Psychiatry and Neurosciences (INSERM/Paris Descartes, Paris) under the direction of Jacques Pantel, which I am currently completing in Florence Noble’s team. My PhD project is focused on a neuroendocrine system – acyl ghrelin & its receptor, the GHSR – implicated in energy homeostasis. We use a novel Ghsr mutant rat model to assess the physiological relevance of GHSR signaling pathways in metabolism, homeostatic & hedonic feeding behavior, as well as hippocampal-dependent memory.
- 2014-2017 PhD in Neuroendocrinology – INSERM/Paris Descartes
“Roles of the ghrelin receptor in the physiopathology of eating behavior”
- 2013-2014 Master 2 Nutrition and Health (MSc.) – AgroParisTech
- 2011-2014 Master of Engineering in Agronomy and Food sciences (MSc. Eng.) – AgroParisTech
- Three Novel Candidate Probiotic Strains with Prophylactic Properties in a Murine Model of Cow\\’s Milk Allergy.
Neau E, Delannoy J, Marion C, Cottart CH, Labellie C, Holowacz S, Butel MJ, Kapel N, Waligora-Dupriet AJ : Appl Environ Microbiol, 2016
- Enhanced responsiveness of Ghsr Q343X rats to ghrelin results in enhanced adiposity without increased appetite.
Chebani Y, Marion C, Zizzari P, Chettab K, Pastor M, Korostelev M, Geny D, Epelbaum J, Tolle V, Morisset-Lopez S, Pantel J : Sci Signal, 2016